Optical microscope with tethered particle motion set-up

Brand: 
Nikon Diaphot 300
Facility nickname: 
TPM
Facility category: 
Light microscopy
Status: 
Operational
Contact person: 
Remus Dame
Optical microscope with tethered particle motion set-up

This set-up allows
measuring physical properties of single molecules in an aqueous environment.
One end of for instance a DNA molecule is attached to a surface and the other
end is attached to a small bead. By following the movement of the bead with a
microscope you get information about physical properties and interactions.  

Use: 

studying protein-DNA interactions

Features: 
  • Heating stage (up to 55 degrees)
    Flow cell
Last Modified: 23-06-2011