light microscopy

Facility

Inverted confocal microscope with DIC

Inverted confocal microscope with perfect focus system, standard and spectral detector and solent incubato.

Confocal laser scanning microscope with two photon set-up

Inverted Confocal Laser Scanning Microscope

High throughput spinning disc

The BD pathway is suited for high throughput epifluorescence, transmitted light and Nipkow spinning disc confocal imaging.

The machine has been used for live imaging of apoptosis, cell proliferation and transcription factor dynamics. Another application is imaging and quantification of immunostained cells (e.g. DNA damage, NF-kB nuclear translocation, EGFR signaling, 3D tubulogenesis).

Injection microscope

Regular light microscope with injection set-up

Confocal microscope with TIRF unit

Live imaging fluorescence microscope

Fluorescence microscope

Facility category

Light microscopy

Light microscopy is the oldest form of microscopy and is based on visible light and lenses. Light microscopes can make use of the absorption or interference of light with a specimen in order to create an image. Fluorescent probes play a major role in the field of light microscopy. These so-called fluorophores enable us to study processes in living cells that cannot be visualized using other methods.